Possible modulators of this effect include VD, temperature, ultraviolet A (UVA) radiation and ultraviolet B (UVB) light radiation. In order to reduce the medication burden it may be worthwhile examining readily modifiable risk factors such as insufficient sun exposure and vitamin D (VD) deficiency, both of which play a role in blood pressure homeostasis.Įpidemiological studies have shown that blood pressure correlates with geographical latitude, and that sunlight exposure might reduce both blood pressure and CVD. Older people with CVD usually have multiple chronic conditions which are often addressed by guidelines that focus on a single disease, an approach that can increase the risk of inappropriate polypharmacy. Its prevalence increases with older age, reaching 80% in people above the age of 75. Hypertension is a major risk factor for cardiovascular disease (CVD). Future studies will be needed to determine the effect of UV light in different samples of the population and especially in a population with hypertension.
UV light had only a short-term effect but not a long-term effect on blood pressure reduction compared to VD use in this sample of normotensive to mild hypertensive nursing home residents with dementia.
With the VD group as a reference, the estimated difference in mean change of systolic blood pressure was − 26.0 mmHg at 1 month, 4.5 mmHg (95% CI -6.8, 15.9, p = 0.432) at 3 months, and 0.1 (95% CI -14.1, 14.3, p = 0.83) at 6 months. Differences in blood pressure changes were assessed using linear mixed models. Short-term effects were evaluated after 1 month and long-term effects after 3 and 6 months. The participants received half-body UV irradiation, twice weekly over 6 months, at one standard erythema dose (UV group, n = 22) or 5600 international units of cholecalciferol once a week (VD group, n = 39).
Post-hoc analysis of randomized controlled trial data concerning nursing home residents with dementia ( N = 61 41 women, mean age 84.8 years). The aim of this study was to assess differences in blood pressure changes between persons with dementia receiving UV light versus vitamin D (VD) supplementation. Observational studies have reported an inverse association between ultraviolet (UV) radiation and hypertension.
0 kommentar(er)
